The point of farming melee creatures is that they mob you (which is a good thing). Then, a Triple Chop/Cyclone Axe will hit each and every creature. This gains your tons of life (with a Vampiric Axe, Live Vicariously, and Vigorous Spirit), builds up a ton of adrenaline (to fuel Executioner's Strike, Bonetti's Defense, etc. after just 1 swing), and/or builds up a ton of energy (with a Zealous Axe). Additionally, but less important, is that your armor is best against physical damage and absorption actually works. Also, one of the keys to farming is the amount of time taken, and melee creatures are fairly quick to dispose of with Triple Chop, etc.
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